Comparison of In Vitro Activities of Voriconazole and Five Established Antifungal Agents against Different Species of Dermatophytes Using a Broth Macrodilution Method-Reference-Cited by-同舟云学术

Comparison of In Vitro Activities of Voriconazole and Five Established Antifungal Agents against Different Species of Dermatophytes Using a Broth Macrodilution Method

Published:2001-01 Issue:1 Volume:39 Page:385-388
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Perea Sofia¹,Fothergill Annette W.¹,Sutton Deanna A.¹,Rinaldi Michael G.¹²

Affiliation:

1. Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78284-7881,1 and

2. Audie Murphy Division, South Texas Veterans Health Care System, San Antonio, Texas 78284-77502

Abstract

ABSTRACT The in vitro activities of voriconazole against 19 different species of dermatophytes were compared with those of terbinafine, itraconazole, ketoconazole, griseofulvin, and fluconazole. MICs were determined according to a National Committee for Clinical Laboratory Standards broth macrodilution method. Voriconazole appeared more active than ketoconazole, griseofulvin, and fluconazole and less active than itraconazole and terbinafine. Based on these results, voriconazole merits further investigation as a potentially useful agent for the treatment of dermatophytosis.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.39.1.385-388.2001

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