Comparative Evaluation of Enteric Bacterial Culture and a Molecular Multiplex Syndromic Panel in Children with Acute Gastroenteritis

Author:

Kellner Thomas1,Parsons Brendon23,Chui Linda23,Berenger Byron M.456,Xie Jianling7,Burnham Carey-Ann D.8,Tarr Phillip I.9,Lee Bonita E.10,Nettel-Aguirre Alberto111213,Szelewicki Jonas23,Vanderkooi Otto G.14151617,Pang Xiao-Li23,Zelyas Nathan1819,Freedman Stephen B.2021ORCID

Affiliation:

1. Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

2. Public Health Laboratory (ProvLab), Alberta Public Laboratories, Edmonton, Alberta, Canada

3. Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada

4. Department of Pathology and Laboratory Medicine, Alberta Public Laboratories, Calgary, Alberta, Canada

5. Calgary Laboratory Services, Calgary, Alberta, Canada

6. Public Health Laboratory (ProvLab), Alberta Public Laboratories, Calgary, Alberta, Canada

7. Section of Pediatric Emergency Medicine, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

8. Department of Pathology & Immunology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA

9. Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA

10. Department of Pediatrics, Faculty of Medicine and Dentistry, Women and Children's Health Research Institute, University of Alberta, Edmonton, Alberta, Canada

11. Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

12. Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

13. Faculty of Kinesiology, Alberta Children's Hospital Research Institute, O'Brien Population Health Institute, University of Calgary, Calgary, Alberta, Canada

14. Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada

15. Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada

16. Department of Pathology & Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada

17. Department of Community Health Sciences, Alberta Children’s Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

18. Department of Medical Microbiology and Immunology, University of Alberta Edmonton, Alberta, Canada

19. Provincial Laboratory for Public Health, Edmonton, Alberta, Canada

20. Section of Pediatric Emergency Medicine, Department of Pediatrics, Alberta Children’s Hospital, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

21. Section of Pediatric Gastroenterology, Department of Pediatrics, Alberta Children’s Hospital, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

Abstract

Although enteric multianalyte syndromic panels are increasingly employed, direct comparisons with traditional methods and the inclusion of host phenotype correlations are limited. Luminex xTAG gastrointestinal pathogen panel (GPP) and culture results are highly concordant.

Funder

HHS | National Institutes of Health

Alberta Health Services

Alberta Innovates | Alberta Innovates - Health Solutions

U of C | Alberta Children's Hospital Research Institute

Women and Children's Health Research Institute

Alberta Children's Hospital Foundation

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference40 articles.

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