Seroprevalence and Molecular Epidemiology of Human T-Cell Leukemia Virus Type 1 (HTLV-1) and HTLV-2 in Blood Donors from Dakar, Senegal

Author:

Diop Saliou1,Calattini Sara2,Abah-Dakou Julienne1,Thiam Doudou1,Diakhaté Lamine1,Gessain Antoine2

Affiliation:

1. Centre National de Transfusion Sanguine, Ave. Cheikh Anta Diop, Fann, BP 5002 Dakar, Sénégal

2. Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes, Département Ecosytèmes et Epidémiologie des Maladies Infectieuses, Institut Pasteur, 75015 Paris, France

Abstract

ABSTRACT In 2002, human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 seroprevalence was 0.16% (8/4,900) in blood donors from Dakar, Senegal. Most of the positive donors originated from the country’s southern region. Seven donors were infected by HTLV-1 (of cosmopolitan subtype), and one was infected by HTLV-2. These data highlight the problem of transfusion safety in this area where HTLV-1-associated lymphoproliferative and neurological diseases are endemic.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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