Clinical and Public Health Implications of Human T-Lymphotropic Virus Type 1 Infection

Author:

Legrand Nicolas1ORCID,McGregor Skye1,Bull Rowena1,Bajis Sahar1,Valencia Braulio Mark1,Ronnachit Amrita2,Einsiedel Lloyd3,Gessain Antoine4,Kaldor John1,Martinello Marianne1

Affiliation:

1. Kirby Institute, UNSW Sydney, Sydney, New South Wales, Australia

2. Royal Prince Alfred Hospital, Sydney, New South Wales, Australia

3. Central Australian Health Service, Alice Springs, Northern Territory, Australia

4. Institut Pasteur, Epidemiology and Physiopathology of Oncogenic Viruses Unit, Paris, France

Abstract

Human T-lymphotropic virus type 1 (HTLV-1) is estimated to affect 5 to 10 million people globally and can cause severe and potentially fatal disease, including adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The burden of HTLV-1 infection appears to be geographically concentrated, with high prevalence in discrete regions and populations.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,General Immunology and Microbiology,Epidemiology

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