Virology, pathogenesis, epidemiology and clinical management of HTLV-1 infection. Proceedings of the 30th HTLV European research network (HERN 2023)

Author:

de Mendoza Carmen1,Taylor Graham2,Gessain Antoine3,Thoma-Kress Andrea K.4,Bangham Charles2,Vesterbacka Jan5,Accolla Roberto6,Bazarbachi Ali7,van Weyenbergh Johan8,Cook Lucy2,Casseb Jorge9,Ramos Juan Carlos10,Rosadas Carolina2,Macchi Beatrice11,Cassar Olivier3,Soriano Vicente12

Affiliation:

1. Puerta de Hierro University Hospital , Madrid , Spain

2. Imperial College London , London , UK

3. Institut Pasteur , Université Paris Cité and CNRS , Paris , France

4. Friedrich-Alexander-Universität Erlangen-Nürnberg , Erlangen , Germany

5. Karolinska University Hospital , Stockholm , Sweden

6. University of Insubria , Varese , Italy

7. American University of Beirut , Beirut , Lebanon

8. Rega Institute for Medical Research , KU Leuven , Leuven , Belgium

9. University of Sao Paulo Medical School , Sao Paulo , Brazil

10. University of Miami Miller School of Medicine , Miami , FL , USA

11. University of Rome Tor Vergata , Rome , Italy

12. Health Sciences School , Universidad Internacional de La Rioja (UNIR) , Madrid , Spain

Abstract

Abstract The 30th workshop of the HTLV European Research Network (HERN) was held in Madrid on September 15–16, 2023. Over fifty researchers from Europe and America convened for a two-day conference to update and discuss basic science, epidemiology, clinical management and therapeutics for patients with HTLV-1 infection. Scientific topics addressed included new estimates for HTLV-1 in Europe; impact of antenatal screening on mother-to-child HTLV-1 infections; new insights into the molecular epidemiology of HTLV-1; reports of elite controllers for HTLV-1 infection; role of antiretrovirals as HTLV-1 pre-exposure prophylaxis; and prospects for a HTLV-1 vaccine. The group agreed to submit a formal request to WHO for increasing the global surveillance and awareness of HTLV-1. This viral infection is a potentially life-threatening, neglected condition with neither treatment nor vaccine. At this time, expanding HTLV-1 screening is the most effective way to reduce viral dissemination.

Publisher

Walter de Gruyter GmbH

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