Characterization of the 6′- N -Aminoglycoside Acetyltransferase Gene aac(6′)-Iq from the Integron of a Natural Multiresistance Plasmid-Reference-Cited by-同舟云学术

Characterization of the 6′- N -Aminoglycoside Acetyltransferase Gene aac(6′)-Iq from the Integron of a Natural Multiresistance Plasmid

Published:1998-06 Issue:6 Volume:42 Page:1506-1508
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Centrón Daniela¹²³,Roy Paul H.¹²

Affiliation:

1. Département de Biochimie, Faculté des Sciences et de Génie, Université Laval, Sainte-Foy, Québec, Canada G1K 7P41;

2. Centre de Recherche en Infectiologie, Centre de Recherche du CHUL, Sainte-Foy, Québec, Canada G1V 4G22; and

3. Facultad de Medicina de la Universidad de Buenos Aires, (1121) Capital Federal, Argentina3

Abstract

ABSTRACT The nucleotide sequence of a newly identified amikacin resistance gene, aac(6′)-Iq (551 bp), is reported. It has 68.4 and 94.4% homology with the aac(6′)-Ia gene and the recently described aac(6′)-Ip gene, respectively. Analysis of its flanking sequences indicated that it is in the first cassette of a class I integron and has an attC site (59-base element) 108 bp in length.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.42.6.1506

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3. Characterization of the chromosomal aac(6')-Ii gene specific for Enterococcus faecium

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