Serum dilution neutralization test for California group virus identification and serology

Author:

Lindsey H S,Calisher C H,Mathews J H

Abstract

The serum dilution neutralization test was evaluated for serological diagnosis of California group arbovirus infections and identification of virus isolates. The technical advantages and the degree of subtype specificity of the serum dilution neutralization test over the hemagglutination inhibition test and the complement fixation test were demonstrated with paired specimens from human cases, single human survey sera, and sentinel rabbit sera. Twenty-one virus isolates from various geographical areas of the United States were also used to evaluate the efficacy of the serum dilution neutralization test for specific virus identification.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference12 articles.

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5. The growing importance of California arboviruses in the etiology of human disease;Henderson B. E.;Prog. Med. Virol.,1971

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