Infectivity of Plasmodium berghei Sporozoites Delivered by Intravenous Inoculation versus Mosquito Bite: Implications for Sporozoite Vaccine Trials-Reference-Cited by-同舟云学术

Infectivity of Plasmodium berghei Sporozoites Delivered by Intravenous Inoculation versus Mosquito Bite: Implications for Sporozoite Vaccine Trials

Published:1999-08 Issue:8 Volume:67 Page:4285-4289
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Vaughan Jefferson A.¹,Scheller Libia F.¹,Wirtz Robert A.¹,Azad Abdu F.¹

Affiliation:

1. Department of Microbiology & Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201

Abstract

ABSTRACT Plasmodium berghei sporozoites delivered by mosquito bite were more infectious to outbred CD-1 mice than were sporozoites delivered by intravenous inoculation. The route of challenge also affected vaccine efficacy. In view of these findings and the fact that mosquito bites are the natural mode of sporozoite delivery, infectious mosquito bites should be considered the challenge protocol of choice for sporozoite vaccine efficacy trials.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.67.8.4285-4289.1999

Reference56 articles.

1. Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi;Anders R. F.;Vaccine,1998

2. Protection of Mice against Plasmodium yoelii Sporozoite Challenge with P. yoelii Merozoite Surface Protein 1 DNA Vaccines

3. Quantitation of Plasmodium falciparum sporozoites transmitted by experimentally infected Anopheles gambiae and Anopheles stephensi;Beier J. C.;Am. J. Trop. Med. Hyg.,1991

4. Sporozoite transmission by Anopheles freeborni and Anopheles gambiae experimentally infected with Plasmodium falciparum;Beier J. C.;J. Am. Mosq. Control Assoc.,1992

5. Ingestion of Plasmodium falciparum sporozoites during transmission by anopheline mosquitoes;Beier M. S.;Am. J. Trop. Med. Hyg.,1992

Cited by 65 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Therapeutic Targeting and Role of Cysteine Proteases in the Life Cycle of Malaria Parasite;Current Medicinal Chemistry;2024-08-23

2. Host skin immunity to arthropod vector bites: from mice to humans;Frontiers in Tropical Diseases;2024-05-01

3. Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria;2023-08-11

4. Novel approaches for the rapid development of rationally designed arbovirus vaccines;One Health;2023-06

5. Malaria: influence of Anopheles mosquito saliva on Plasmodium infection;Trends in Immunology;2023-04