Protection of Mice against Plasmodium yoelii Sporozoite Challenge with P. yoelii Merozoite Surface Protein 1 DNA Vaccines-Reference-Cited by-同舟云学术

Protection of Mice against Plasmodium yoelii Sporozoite Challenge with P. yoelii Merozoite Surface Protein 1 DNA Vaccines

Published:1998-07 Issue:7 Volume:66 Page:3457-3461
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Becker Sylvia I.¹,Wang Ruobing¹,Hedstrom Richard C.¹,Aguiar Joao C.¹²,Jones Trevor R.¹,Hoffman Stephen L.¹,Gardner Malcolm J.¹³

Affiliation:

1. Malaria Program, Naval Medical Research Institute, Bethesda, Maryland 20889-56071;

2. Pan American Health Organization, Washington, D.C. 200372; and

3. Department of Microbiology and Immunology, University of Maryland at Baltimore, Baltimore, Maryland 21201-15593

Abstract

ABSTRACT Immunization of mice with DNA vaccines encoding the full-length form and C and N termini of Plasmodium yoelii merozoite surface protein 1 provided partial protection against sporozoite challenge and resulted in boosting of antibody titers after challenge. In C57BL/6 mice, two DNA vaccines provided protection comparable to that of recombinant protein consisting of the C terminus in Freund’s adjuvant.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.66.7.3457-3461.1998

Reference25 articles.

1. A protective monoclonal antibody recognizes an epitope in the carboxyl-terminal cysteine-rich domain in the precursor of the major merozoite surface antigen of the rodent malarial parasite, Plasmodium yoelii.;Burns J. M.;J. Immunol.,1989

2. A recombinant baculovirus 42-kilodalton C-terminal fragment of Plasmodium falciparum merozoite surface protein 1 protects Aotus monkeys against malaria

3. Humoral response to a carboxyl-terminal region of the merozoite surface protein-1 plays a predominant role in controlling blood-stage infection in rodent malaria.;Daly T. M.;J. Immunol.,1995

4. Influence of adjuvants on protection induced by a recombinant fusion protein against malarial infection

5. A recombinant 15-kilodalton carboxyl-terminal fragment of Plasmodium yoelii yoelii 17XL merozoite surface protein 1 induces a protective immune response in mice

Cited by 38 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Preclinical Development and Assessment of Viral Vectors Expressing a Fusion Antigen of Plasmodium falciparum LSA1 and LSAP2 for Efficacy against Liver-Stage Malaria;Infection and Immunity;2020-01-22

2. DNA-Loaded Cationic Liposomes Efficiently Function as a Vaccine against Malarial Proteins;Molecular Therapy - Methods & Clinical Development;2017-12

3. Immunogenicity of a plasmid DNA vaccine encoding 42 kDa fragment of Plasmodium vivax merozoite surface protein-1;Acta Tropica;2016-10

4. Plasmodium falciparum double C2 domain protein, PfDOC2, binds to calcium when associated with membranes;Experimental Parasitology;2014-09

5. Molecular Delivery of Plasmids for Genetic Vaccination;Current Pharmaceutical Biotechnology;2013-11