Rrp2, a σ 54 -Dependent Transcriptional Activator of Borrelia burgdorferi , Activates rpoS in an Enhancer-Independent Manner-Reference-Cited by-同舟云学术

Rrp2, a σ 54 -Dependent Transcriptional Activator of Borrelia burgdorferi , Activates rpoS in an Enhancer-Independent Manner

Published:2009-04-15 Issue:8 Volume:191 Page:2902-2905
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Blevins Jon S.¹²,Xu Haijun³,He Ming³,Norgard Michael V.²,Reitzer Larry⁴,Yang X. Frank³

Affiliation:

1. Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205

2. Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390

3. Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202

4. Department of Molecular and Cell Biology, University of Texas at Dallas, Richardson, Texas 75083

Abstract

ABSTRACT Rrp2 is the sole σ 54 -dependent transcriptional activator present in the Borrelia burgdorferi genome. We showed that recombinant Rrp2 binds to DNA in a sequence-nonspecific manner. During infection, Rrp2 activates σ 54 -dependent rpoS expression without an apparent upstream enhancer element commonly associated with other σ 54 -dependent transcriptional activators.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.01721-08

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