<i>Pf</i> ARID Regulates P. falciparum Malaria Parasite Male Gametogenesis and Female Fertility and Is Critical for Parasite Transmission to the Mosquito Vector-Reference-Cited by-同舟云学术

Pf ARID Regulates P. falciparum Malaria Parasite Male Gametogenesis and Female Fertility and Is Critical for Parasite Transmission to the Mosquito Vector

Published:2022-06-28 Issue:3 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Kumar Sudhir¹^ORCID,Baranwal Vinay K.²,Haile Meseret T.¹,Oualim Kenza M. Z.¹,Abatiyow Biley A.¹,Kennedy Spencer Y.¹,Vaughan Ashley M.¹³,Kappe Stefan H. I.¹³⁴

Affiliation:

1. Center for Global Infectious Disease Research, Seattle Children’s Research Institute, Seattle, Washington, USA

2. Molecular Botany Lab, Swami Devanand Post Graduate College, Math-Lar, Deoria, Uttar Pradesh, India

3. Department of Pediatrics, University of Washington, Seattle, Washington, USA

4. Department of Global Health, University of Washington, Seattle, Washington, USA

Abstract

Successful completion of the Plasmodium life cycle requires formation of mature gametocytes and their uptake by the female Anopheles mosquito vector in an infected blood meal. Inside the mosquito midgut the parasite undergoes gametogenesis and sexual reproduction.

Funder

Seattle Children's Research Institute

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00578-22

Reference85 articles.

1. Malaria Parasite Development in the Mosquito and Infection of the Mammalian Host

2. Cytology and Kinetics of microgametogenesis and fertilization inPlasmodium yoelii nigeriensis

3. Sexual Development of Malarial Parasites