Susceptibility of Anaerobic Bacteria to Cefoxitin and Related Compounds

Author:

Bach Vinth Toan1,Roy Ira1,Thadepalli Haragopal2

Affiliation:

1. Charles R. Drew Postgraduate School of Medicine, and University of Southern California School of Medicine, Los Angeles, California 90059

2. Department of Internal Medicine, Martin Luther King Jr. General Hospital,Los Angeles, California 90059

Abstract

Cephalothin, cefazolin, cephradine, and cefoxitin inhibited more than 75% of 326 anaerobic bacteria in vitro, but cefoxitin was the most effective against anaerobes in general and Bacteroides fragilis in particular.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference8 articles.

1. Comparison of cefoxitin and cephalothin therapy of a mixed Bacteroides fragilis and Fusobacterium necrophorum infection in mice;Hackman A. S.;Antimicrob. Agents Chemother.,1975

2. In vitro antimicrobial susceptibility of anaerobic bacteria isolates from clinical specimens;Martin W. J.;Antimicrob. Agents Chemother.,1972

3. Susceptibility of clinical isolates of bacteria to cefoxitin and cephalothin;Moellering R. C.;Antimicrob. Agents Chemother.,1974

4. Cefoxitin, a semisynthetic cephamycin antibiotic: antibacterial spectrum and resistance to hydrolysis by gram-negative beta-lactamases;Neu H. C.;Antimicrob. Agents Chemother.,1974

5. In vitro susceptibility of anaerobes to ticarcillin;Roy I.;Antimicrob. Agents Chemother.,1977

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