Abstract
Streptococcus faecalis strain DS-5 has been shown previously to contain three plasmids, pAMalpha1, pAMbeta1, and pAMgamma1. Mixed incubation of DS-5 with strain JH2-2, a plasmid-free S. faecalis recipient, results in the transfer of pAMalpha1 (which determines resistance to tetracycline) and/or pAMgamma1. Analyses of recipients carrying various combinations of these plasmids have revealed the pAMgamma1 codes for toxin (hemolysin) production and two bacteriocin activities. JH2-2 strains carrying both pAMalpha1 and pAMgamma1, or pAMgamma1 only, can donate their plasmids to other recipients, whereas strains carrying only pAMalpha1 cannot serve as donors. This indicates that pAMgamma1 actually mobilizes the otherwise nontransferable pAMalpha1.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference20 articles.
1. Characterization of a transfer factor associated with drug resistance in Salmonella typhimurium;Anderson E. S.;Nature (London),1965
2. Bacterial genome sizes determined by DNA renaturation studies;Bak A. L.;J. Gen. Microbiol.,1970
3. Probable identity of a group D hemolysin with a bacteriocine;Brock T.;J. Bacteriol.,1963
4. Nature of Col E, plasmid replication in Escherichia coli in the presence of chloramphenicol;Clewell D. B.;J. Bacteriol.,1972
5. Characterization of a plasmid determining resistance to erythromycin, lincomycin, and vernamycin B,, in a strain of Streptococcus pyogenes;Clewell D. B.;Antimicrob. Agents Chemother.,1974
Cited by
172 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献