PROBABLE IDENTITY OF A GROUP D HEMOLYSIN WITH A BACTERIOCINE

Author:

Brock Thomas D.1,Davie Joseph M.1

Affiliation:

1. Department of Bacteriology, Indiana University, Bloomington, Indiana

Abstract

Brock, Thomas D. (Indiana University, Bloomington) and Joseph M. Davie . Probable identity of a group D hemolysin with a bacteriocine. J. Bacteriol. 86: 708–712. 1963.—All strains of Streptococcus zymogenes ( S. faecalis var. zymogenes ) produce a bacteriocine which is active against lactic acid bacteria and most other grampositive bacteria. Mutants which have lost the hemolytic characteristic lose at the same time their bacteriocine-producing ability. A strain which was resistant to the bacteriocine but which was nonhemolytic and nonbacteriocinogenic was irradiated, and two hemolytic mutants were isolated from it. These mutants were also bacteriocinogenic. Thus, the two activities are gained or lost together by mutation. Both activities are destroyed by chloroform vapors and are antagonized by lecithin. Both activities are destroyed at the same rate by treatment at 45 C under mildly acid conditions, and both activities are stable when heated in agar. The two activities are produced in parallel during the growth cycle, and disappear in parallel. The possible ecological role of a substance which is both a hemolysin and a bacteriocine is discussed.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference5 articles.

1. BERNHEIMER A. W. 1954. Streptolysins and their inhibitors p. 21. In M. McCarty [ed.] Streptococcal infections. Columbia University Press New York.

2. Survey of the bacteriocines of enterococci;BROCK T. D.;J. Bacteriol.,1963

3. Titration and partial characterization of a soluble hemolysin of a group D streptococcus;IRWIN J.;J. Bacteriol.,1958

4. Studies on streptococci. III. New antibiotic substances produced by beta hemolytic streptococci;SHERWOOD N. B.;J. Infect. Diseases,1949

5. Antibiotic activity of hemolytic enterococci;STARK J. M.;Lancet,1960

Cited by 102 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3