The Phosphatase Bph and Peptidyl-Prolyl Isomerase PrsA Are Required for Gelatinase Expression and Activity in Enterococcus faecalis-Reference-Cited by-同舟云学术

The Phosphatase Bph and Peptidyl-Prolyl Isomerase PrsA Are Required for Gelatinase Expression and Activity in Enterococcus faecalis

Published:2022-07-19 Issue:7 Volume:204 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Willett Julia L. E.¹,Robertson Ethan B.¹,Dunny Gary M.¹

Affiliation:

1. Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, Minnesota, USA

Abstract

In Enterococcus faecalis , gelatinase (GelE) is a virulence factor that is also important for biofilm formation and interactions with other microbes as well as the host immune system. The long-standing model for GelE production is that the Fsr quorum sensing system positively regulates expression of gelE .

Funder

HHS | NIH | National Center for Advancing Translational Sciences

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.00129-22

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1. Genomic transition of enterococci from gut commensals to leading causes of multidrug-resistant hospital infection in the antibiotic era

2. Biofilm-associated infection by enterococci