Evaluation of Metabolic Engineering Strategies on 2-Ketoisovalerate Production by Escherichia coli

Author:

Zhou Li1ORCID,Zhu Ying1,Yuan Zhongzhe1,Liu Guangqing1,Sun Zijin1,Du Shiyu1,Liu He1,Li Yating1,Liu Haili1,Zhou Zhemin1ORCID

Affiliation:

1. The Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, People’s Republic of China

Abstract

An efficient microbial strain was constructed for 2-ketoisovalerate synthesis. The positive effect of the leuA deletion on 2-ketoisovalerate production was found.

Funder

MOST | National Key Research and Development Program of China

National Natural Science Foundation of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

the jiangsu province “collaborative innovation center for advanced industrial fermentation” industry development program

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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