Solanimycin: Biosynthesis and Distribution of a New Antifungal Antibiotic Regulated by Two Quorum-Sensing Systems-Reference-Cited by-同舟云学术

Solanimycin: Biosynthesis and Distribution of a New Antifungal Antibiotic Regulated by Two Quorum-Sensing Systems

Published:2022-12-20 Issue:6 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Matilla Miguel A.¹²,Monson Rita E.¹,Murphy Annabel³,Schicketanz Muriel¹,Rawlinson Alison¹,Duncan Caia¹,Mata Juan¹,Leeper Finian³,Salmond George P. C.¹

Affiliation:

1. Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

2. Department of Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Granada, Spain

3. Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, United Kingdom

Abstract

Fungal infections represent a major clinical, agricultural, and food security threat worldwide, which is accentuated due to the difficult treatment of these infections. Microorganisms represent a prolific source of antibiotics, and current data support that this enormous biosynthetic potential has been scarcely explored.

Funder

UKRI | Biotechnology and Biological Sciences Research Council

EC | FP7 | People | FP7 People: Marie-Curie Actions

MEC | Spanish National Plan for Scientific and Technical Research and Innovation

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.02472-22

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1. Natural Products as Sources of New Drugs from 1981 to 2014