A Computational Toolbox to Investigate the Metabolic Potential and Resource Allocation in Fission Yeast

Author:

Grigaitis Pranas1ORCID,Grundel Douwe A. J.1,van Pelt-KleinJan Eunice12,Isaku Mirushe1,Xie Guixiang1,Mendoza Farias Sebastian1,Teusink Bas1ORCID,van Heerden Johan H.1ORCID

Affiliation:

1. Systems Biology Lab, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

2. TiFN, Wageningen, The Netherlands

Abstract

Our understanding of microbial metabolism relies mostly on the knowledge we have obtained from a limited number of model organisms, and the diversity of metabolism beyond the handful of model species thus remains largely unexplored in mechanistic terms. Computational modeling of metabolic networks offers an attractive platform to bridge the knowledge gap and gain new insights into physiology of lesser-studied organisms.

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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