Population Pharmacokinetics of Dalbavancin and Dosing Consideration for Optimal Treatment of Adult Patients with Staphylococcal Osteoarticular Infections-Reference-Cited by-同舟云学术

Population Pharmacokinetics of Dalbavancin and Dosing Consideration for Optimal Treatment of Adult Patients with Staphylococcal Osteoarticular Infections

Published:2021-04-19 Issue:5 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Cojutti Pier Giorgio¹²,Rinaldi Matteo³⁴,Zamparini Eleonora³⁴,Rossi Nicolò³⁴,Tedeschi Sara³⁴,Conti Matteo³,Pea Federico³⁵^ORCID,Viale Pierluigi³⁴

Affiliation:

1. Department of Medicine, University of Udine, Udine, Italy

2. Institute of Clinical Pharmacology, Santa Maria della Misericordia University Hospital of Udine, ASUFC, Udine, Italy

3. Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy

4. Infectious Diseases Unit, IRCCS Sant' Orsola Teaching Hospital, Bologna, Italy

5. SSD Clinical Pharmacology Unit, IRCCS Sant' Orsola Teaching Hospital, Bologna, Italy

Abstract

Dalbavancin is gaining interest in the treatment of complex osteoarticular (OA) infections. We aimed to conduct a population pharmacokinetic analysis of dalbavancin in a prospective cohort of adult patients with OA infections caused by Gram-positive organisms and to identify optimal dosing regimens for long-term treatment.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02260-20

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