Prosthetic Joint Infection

Author:

Tande Aaron J.1,Patel Robin12

Affiliation:

1. Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA

2. Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA

Abstract

SUMMARY Prosthetic joint infection (PJI) is a tremendous burden for individual patients as well as the global health care industry. While a small minority of joint arthroplasties will become infected, appropriate recognition and management are critical to preserve or restore adequate function and prevent excess morbidity. In this review, we describe the reported risk factors for and clinical manifestations of PJI. We discuss the pathogenesis of PJI and the numerous microorganisms that can cause this devastating infection. The recently proposed consensus definitions of PJI and approaches to accurate diagnosis are reviewed in detail. An overview of the treatment and prevention of this challenging condition is provided.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,General Immunology and Microbiology,Epidemiology

Reference472 articles.

1. Centers for Disease Control and Prevention. 2013. National hospital discharge survey: 2010 table, procedures by selected patient characteristics. Centers for Disease Control and Prevention, Atlanta, GA. http://www.cdc.gov/nchs/data/nhds/4procedures/2010pro4_numberprocedureage.pdf .

2. Projections of Primary and Revision Hip and Knee Arthroplasty in the United States from 2005 to 2030

3. The Nordic Arthroplasty Register Association

4. Knee arthroplasty in Denmark, Norway and Sweden

5. Economic Burden of Periprosthetic Joint Infection in the United States

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