Antimicrobial Treatment and Containment Measures for an Extremely Drug-Resistant Klebsiella pneumoniae ST101 Isolate Carrying pKPN101-IT, a Novel Fully Sequenced bla KPC-2 Plasmid-Reference-Cited by-同舟云学术

Antimicrobial Treatment and Containment Measures for an Extremely Drug-Resistant Klebsiella pneumoniae ST101 Isolate Carrying pKPN101-IT, a Novel Fully Sequenced bla KPC-2 Plasmid

Published:2012-11 Issue:11 Volume:50 Page:3768-3772
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Frasson Ilaria¹,Lavezzo Enrico¹,Franchin Elisa¹²,Toppo Stefano¹,Barzon Luisa¹²,Cavallaro Antonietta²,Richter Sara N.¹²,Palù Giorgio¹²

Affiliation:

1. Department of Molecular Medicine, Padua, Italy

2. Azienda Ospedaliera di Padova, Microbiology and Virology Unit, Padua, Italy

Abstract

ABSTRACT An extremely drug-resistant Klebsiella pneumoniae isolate, sequence type ST101, was isolated from a patient in Italy. We describe antibiotic treatment, measures to clear and contain the infection, and a complete sequence analysis of a novel large plasmid, pKPN101-IT, harboring the bla KPC-2 gene and arising from the threatening recombination of different worldwide-distributed backbones.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01892-12

Reference31 articles.

1. Dissemination ofblaKPC-2by the Spread of Klebsiella pneumoniae Clonal Complex 258 Clones (ST258, ST11, ST437) and Plasmids (IncFII, IncN, IncL/M) among Enterobacteriaceae Species in Brazil

2. The RAST Server: Rapid Annotations using Subsystems Technology

3. Characterization of an IncFII Plasmid Encoding NDM-1 from Escherichia coli ST131

4. Complete Nucleotide Sequence of a 92-Kilobase Plasmid Harboring the CTX-M-15 Extended-Spectrum Beta-Lactamase Involved in an Outbreak in Long-Term-Care Facilities in Toronto, Canada

5. Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe;Canton R;Clin. Microbiol. Infect.,2012

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