Antimicrobial Resistance in ESKAPE Pathogens

Author:

De Oliveira David M. P.12,Forde Brian M.12ORCID,Kidd Timothy J.12,Harris Patrick N. A.23,Schembri Mark A.12ORCID,Beatson Scott A.12ORCID,Paterson David L.23,Walker Mark J.12

Affiliation:

1. School of Chemistry and Molecular Biosciences, The University of Queensland, QLD, Australia

2. Australian Infectious Diseases Research Centre, The University of Queensland, QLD, Australia

3. UQ Centre for Clinical Research, The University of Queensland, QLD, Australia

Abstract

Antimicrobial-resistant ESKAPE ( E nterococcus faecium , S taphylococcus aureus , K lebsiella pneumoniae , A cinetobacter baumannii , P seudomonas aeruginosa , and E nterobacter species) pathogens represent a global threat to human health. The acquisition of antimicrobial resistance genes by ESKAPE pathogens has reduced the treatment options for serious infections, increased the burden of disease, and increased death rates due to treatment failure and requires a coordinated global response for antimicrobial resistance surveillance.

Funder

Department of Health | National Health and Medical Research Council

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,General Immunology and Microbiology,Epidemiology

Reference573 articles.

1. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance

2. Prediction of antibiotic resistance: time for a new preclinical paradigm?

3. World Health Organization. 2014. Antimicrobial resistance: global report on surveillance 2014. https://www.who.int/antimicrobial-resistance/publications/surveillancereport/en/. Accessed 26 June 2019.

4. Centers for Disease Control and Prevention. 2019. Antibiotic resistant threats in the United States 2019. https://www.cdc.gov/drugresistance/pdf/threats-report/2019-ar-threats-report-508.pdf. Accessed 15 January 2020.

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