Targeted Conservative Cointegrate Formation Mediated by IS 26 Family Members Requires Sequence Identity at the Reacting End-Reference-Cited by-同舟云学术

Targeted Conservative Cointegrate Formation Mediated by IS 26 Family Members Requires Sequence Identity at the Reacting End

Published:2021-02-24 Issue:1 Volume:6 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Harmer Christopher J.¹^ORCID,Hall Ruth M.¹^ORCID

Affiliation:

1. School of Life and Environmental Sciences, The University of Sydney, NSW, Australia

Abstract

The IS 26 family includes the ISs that are commonly found associated with antibiotic resistance genes in multiply resistant Gram-negative and Gram-positive bacteria. IS 26 is most prevalent in Gram-negative species and can generate the clusters of antibiotic resistance genes interspersed with directly oriented IS 26 seen in multiply resistant pathogens.

Funder

Department of Health, Australian Government | National Health and Medical Research Council

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.01321-20

Reference22 articles.

1. An analysis of the IS6/IS26 family of insertion sequences: is it a single family?

2. Mobile Genetic Elements Associated with Antimicrobial Resistance

3. Functional characterization of the prokaryotic mobile genetic element IS26