Clustering and Erratic Movement Patterns of Syringe-Injected versus Mosquito-Inoculated Malaria Sporozoites Underlie Decreased Infectivity-Reference-Cited by-同舟云学术

Clustering and Erratic Movement Patterns of Syringe-Injected versus Mosquito-Inoculated Malaria Sporozoites Underlie Decreased Infectivity

Published:2021-04-28 Issue:2 Volume:6 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

de Korne C. M.¹²,Winkel B. M. F.¹,van Oosterom M. N.²,Chevalley-Maurel S.¹,Houwing H. M.²,Sijtsma J. C.¹,Azargoshasb S.²,Baalbergen E.¹,Franke-Fayard B. M. D.¹,van Leeuwen F. W. B.²,Roestenberg M.¹³^ORCID

Affiliation:

1. Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands

2. Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands

3. Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

Abstract

Malaria still causes a major burden on global health and the economy. The efficacy of live, attenuated malaria sporozoites as vaccine candidates critically depends on their ability to migrate to and infect the host liver.

Funder

ZonMw

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00218-21

Reference44 articles.

1. Progress with Plasmodium falciparum sporozoite (PfSPZ)-based malaria vaccines

2. Immunity to falciparum and vivax malaria induced by irradiated sporozoites—a review of the University of Maryland Studies, 1971–75;Clyde DF;Bull World Health Org,1990

3. Protection of Humans against Malaria by Immunization with Radiation‐AttenuatedPlasmodium falciparumSporozoites

4. Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8+ T Cell Immunity

5. Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Plasmodium sporozoite shows distinct motility patterns in responses to three-dimensional environments;iScience;2024-08

2. Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria;Scientific Reports;2024-02-04

3. Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria;2023-08-11

4. Artificial Intelligence‐Supported Video Analysis as a Means to Assess the Impact of DROP‐IN Image Guidance on Robotic Surgeons: Radioguided Sentinel Lymph Node versus PSMA‐Targeted Prostate Cancer Surgery;Advanced Intelligent Systems;2023-07-09

5. Malaria: influence of Anopheles mosquito saliva on Plasmodium infection;Trends in Immunology;2023-04