Infection with Toxin A-Negative, Toxin B-Negative, Binary Toxin-Positive Clostridium difficile in a Young Patient with Ulcerative Colitis

Author:

Androga Grace O.1,Hart Julie2,Foster Niki F.12,Charles Adrian3,Forbes David34,Riley Thomas V.12

Affiliation:

1. School of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia

2. Department of Microbiology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia

3. Princess Margaret Hospital for Children, Subiaco, Western Australia, Australia

4. School of Paediatrics and Child Health, The University of Western Australia, Crawley, Western Australia, Australia

Abstract

ABSTRACT Large clostridial toxin-negative, binary toxin-positive (A B CDT + ) strains of Clostridium difficile are almost never associated with clinically significant C. difficile infection (CDI), possibly because such strains are not detected by most diagnostic methods. We report the isolation of an A B CDT + ribotype 033 (RT033) strain of C. difficile from a young patient with ulcerative colitis and severe diarrhea.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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