Clostridium diffi cile infection and its eff ect on the course of infl ammatory bowel diseases-Reference-Cited by-同舟云学术

Clostridium diffi cile infection and its eff ect on the course of infl ammatory bowel diseases

Published:2022-10-30 Issue:7-8 Volume:100 Page:346-356
ISSN:2412-1339
Container-title:Clinical Medicine (Russian Journal)
language:
Short-container-title:jour

Author:

Purgina D. S.¹,Lyalina L. V.²,Rassokhin V. V.³

Affiliation:

1. "Lahta Clinic"

2. St. Petersburg Scientifi c Research Institute of Epidemiology and Microbiology named after Pasteur; North-Western State Medical University named after I.I. Mechnikov of the Ministry of Healthcare of Russia

3. St. Petersburg Scientifi c Research Institute of Epidemiology and Microbiology named after Pasteur; Academician I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of Russia

Abstract

Infl ammatory bowel diseases (IBD) are common autoimmune diseases with gastrointestinal and extra-intestinal manifestations and complications. The most common infectious complication associated with IBD is infection with Clostridium diffi cile (C. diffi cile). Active IBD predisposes to C. diffi cile infection due to changes in the intestinal microbiome. C. diffi cile is a toxinproducing bacterium that leads to a worsening of the course of the main IBD, increasing the risk of ineff ective treatment of IBD, increased risk of hospitalization and surgery.

Publisher

Medical Informational Agency Publishers

Subject

General Medicine

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