Affiliation:
1. Institute of Parasitology, McGill University, Ste. Anne de Bellevue, Quebec, Canada H9X 3V9
Abstract
ABSTRACT
Degradation of the mucus layer by
Entamoeba histolytica
is a prerequisite for invasion of the colonic mucosa. In this study, we demonstrate that amoeba-secreted products degrade
3
H-labeled and native colonic mucin oligosaccharides independently of proteolytic activity. We conclude that
E. histolytica
degrades mucin oligosaccharides, which may facilitate parasite invasion of the colon.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Cited by
34 articles.
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