African strains of Blastomyces dermatitidis that do not express surface adhesin WI-1-Reference-Cited by-同舟云学术

African strains of Blastomyces dermatitidis that do not express surface adhesin WI-1

Published:1997-04 Issue:4 Volume:65 Page:1505-1509
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Klein B S¹,Aizenstein B D¹,Hogan L H¹

Affiliation:

1. Department of Pediatrics, University of Wisconsin Medical School, Madison 53792, USA.

Abstract

African strains of Blastomyces dermatitidis differ from North American strains in their growth, morphology, and clinical disease phenotype. In addition, two serotypes, designated 1 and 2, have been described. We investigated African strains of B. dermatitidis for expression of the surface protein adhesin WI-1 and found that serotype 2 strains do not express it because they lack the coding sequence in their genome. The defect will make the strains useful for gene complementation and for testing the pathogenetic role of the WI-1 adhesin.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.65.4.1505-1509.1997

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