Subtilase Cytotoxin-Encoding subAB Operon Found Exclusively among Shiga Toxin-Producing Escherichia coli Strains

Author:

Irino Kinue1,Vieira Mônica A. Midolli2,Gomes Tânia A. Tardelli2,Guth Beatriz E. Cabilio2,Naves Zita V. Furtado1,Oliveira Murilo Gomes3,dos Santos Luis Fernando2,Guirro Mirian2,Timm Claudio D.4,Pigatto Caroline P.5,Farah Sonia M. S. S.6,Vaz Tânia M. I.1

Affiliation:

1. Department of Bacteriology, Instituto Adolfo Lutz, Av. Dr Arnaldo, 351/355, 9 andar, CEP 01246-902 São Paulo, SP, Brazil

2. Department of Microbiology, Immunology and Parasitology, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brazil

3. Department of Clinical Analysis, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil

4. Department of Preventive Veterinary Medicine, Universidade Federal de Pelotas, Pelotas, Rio Grande do Sul, Brazil

5. Department of Veterinary Medicine, Universidade Federal do Parana, Curitiba, Parana, Brazil

6. Department of Bacteriology, Laboratorio Central de Saude Publica, Curitiba, Parana, Brazil

Abstract

ABSTRACT The presence of subAB was investigated for 3,453 Escherichia coli strains of various pathogenic categories. The occurrence of other virulence genes in subAB -positive strains was investigated. The subAB operon was detected among some Shiga toxin-producing E. coli (STEC) serotypes devoid of eae and carrying ehx A. Most subAB -positive strains also harbored stx 2 , iha , saa , and lpfA O113 .

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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