Measurement of whole body protein turnover by the end-product method.

Abstract

This chapter focuses on the utility of the end-product method, which is based on stochastic analysis, in measuring whole body protein turnover in man. The use of urea, ammonia and respiratory carbon dioxide as end products, and the comparison of oral vs. intravenous and single vs. multiple dosage of tracer are discussed. The variability of the method and its differences with the precursor method are described.