Author:
Brown Anthony,Jenkins Laura,Reid Alastair,Leavy Anne,McDowell Glen,McIlroy Claire,Thompson Andrew,McNaughten Ben
Abstract
Cystic fibrosis (CF) is the most common life-threatening autosomal-recessive disease affecting Caucasians in the western world. The sweat test is the main diagnostic test for CF. It is indicated as part of the clinical assessment for infants that have picked up on the national neonatal screening programme. It may also be requested where clinical suspicion of a diagnosis of CF exists despite normal screening results. This article outlines the physiological basis behind sweat testing and the technical aspects of performing the test. Indications for performing the test are also considered. The article aims to provide clinicians with a guide to interpretation of results.
Subject
Pediatrics, Perinatology and Child Health
Reference19 articles.
1. Data resource profile: the UK cystic fibrosis registry;Taylor-Robinson;Int J Epidemiol,2018
2. Cystic fibrosis
3. Cystic fibrosis
4. Is it cystic fibrosis? the challenges of diagnosing cystic fibrosis;Simmonds;Paediatr Respir Rev,2019
5. Public Health England . A laboratory guide to newborn screening in the UK for cystic fibrosis, 2017. Available: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/397726/Cystic_Fibrosis_Lab_Guide_February_2014_v1.0_12_.pdf [Accessed 01 Oct 2019].
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