Soft, skin-interfaced sweat stickers for cystic fibrosis diagnosis and management

Author:

Ray Tyler R.123ORCID,Ivanovic Maja4,Curtis Paul M.5ORCID,Franklin Daniel23,Guventurk Kerem6ORCID,Jeang William J.3ORCID,Chafetz Joseph3,Gaertner Hannah3ORCID,Young Grace3ORCID,Rebollo Steve7ORCID,Model Jeffrey B.28ORCID,Lee Stephen P.28ORCID,Ciraldo John9ORCID,Reeder Jonathan T.2ORCID,Hourlier-Fargette Aurélie210ORCID,Bandodkar Amay J.2ORCID,Choi Jungil211ORCID,Aranyosi Alexander J.28ORCID,Ghaffari Roozbeh268ORCID,McColley Susanna A.1213ORCID,Haymond Shannon1415,Rogers John A.236816ORCID

Affiliation:

1. Department of Mechanical Engineering, University of Hawaii at Manoa, Honolulu, HI 96822, USA.

2. Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60202, USA.

3. Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60202, USA.

4. Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

5. Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60202, USA.

6. Department of Biomedical Engineering, Northwestern University, Evanston, IL 60202, USA.

7. Pritzker School of Molecular Engineering and Department of Physics, University of Chicago, Chicago, IL 60637, USA.

8. Epicore Biosystems Inc., Cambridge, MA 02139, USA.

9. Micro/Nano Fabrication Facility (NUFAB) Northwestern University, Evanston, IL 60202, USA.

10. Université de Strasbourg, CNRS, Institut Charles Sadron UPR22, F-67000, Strasbourg 67034, France.

11. School of Mechanical Engineering, Kookmin University, Seoul 02707, Republic of Korea.

12. Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

13. Division of Pulmonary and Sleep Medicine, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL 60611, USA.

14. Department of Pathology, Northwestern Feinberg School of Medicine, Chicago, IL 60611, USA.

15. Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL 60611, USA.

16. Department of Mechanical Engineering, Department of Electrical and Computer Engineering, Department of Chemistry, Northwestern University, Evanston, IL 60202, USA.

Abstract

A soft, wearable microfluidic platform collects and quantitatively analyzes sweat biomarkers to improve the diagnosis of cystic fibrosis.

Funder

National Institute on Aging

National Institute of General Medical Sciences

Hawaii Community Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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