Prevalence of aac(6')-Ib-cr plasmid-mediated and chromosome-encoded fluoroquinolone resistance in Enterobacteriaceae in Italy-Reference-Cited by-同舟云学术

Prevalence of aac(6')-Ib-cr plasmid-mediated and chromosome-encoded fluoroquinolone resistance in Enterobacteriaceae in Italy

Published:2011-08-09 Issue:1 Volume:3 Page:
ISSN:1757-4749
Container-title:Gut Pathogens
language:en
Short-container-title:Gut Pathog

Author:

Frasson Ilaria,Cavallaro Antonietta,Bergo Cristina,Richter Sara N,Palù Giorgio

Abstract

Abstract The spread of aac(6')-Ib-cr plasmid-mediated quinolone resistance determinants was evaluated in 197 enterobacterial isolates recovered in an Italian teaching hospital. The aac(6')-Ib-cr gene was found exclusively in Escherichia coli strains. The gene was located on a plasmid which presented additional ESBL genes. Most of the clinical strains were clonally related and displayed three point mutations at the topoisomerase level which conferred high resistance to fluoroquinolones.

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases,Virology,Gastroenterology,Microbiology,Parasitology

Link

https://link.springer.com/content/pdf/10.1186/1757-4749-3-12.pdf

Reference10 articles.

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