Prevalence in the United States of aac(6 ′ ) - Ib - cr Encoding a Ciprofloxacin-Modifying Enzyme-Reference-Cited by-同舟云学术

Prevalence in the United States of aac(6 ′ ) - Ib - cr Encoding a Ciprofloxacin-Modifying Enzyme

Published:2006-11 Issue:11 Volume:50 Page:3953-3955
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Park Chi Hye¹,Robicsek Ari²,Jacoby George A.³,Sahm Daniel⁴,Hooper David C.¹

Affiliation:

1. Massachusetts General Hospital, Boston, Massachusetts

2. Evanston Northwestern Healthcare, Evanston, Illinois

3. Lahey Clinic, Burlington, Massachusetts

4. Focus BioInova, Herndon, Virginia

Abstract

ABSTRACT Among 313 Enterobacteriaceae from the United States with a ciprofloxacin MIC of ≥0.25 μg/ml and reduced susceptibility to ceftazidime, aac(6 ′ )-Ib was present in 50.5% of isolates, and of these, 28% carried the cr variant responsible for low-level ciprofloxacin resistance. aac(6 ′ )-Ib-cr was geographically widespread, stable over time, most common in Escherichia coli , equally prevalent in ciprofloxacin-susceptible and -resistant strains, and not associated with qnr genes.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00915-06

Reference13 articles.

1. Aminoglycoside 6′- N -Acetyltransferase Variants of the Ib Type with Altered Substrate Profile in Clinical Isolates of Enterobacter cloacae and Citrobacter freundii

2. Clinical and Laboratory Standards Institute. 2005. Performance standards for antimicrobial susceptibility testing; 15th informational supplement. CLSI/NCCLS M100-S15. Clinical and Laboratory Standards Institute Wayne Pa.

3. Cloning of a Novel Gene for Quinolone Resistance from a Transferable Plasmid in Shigella flexneri 2b

4. Hooper, D. C. 1999. Mechanisms of quinolone resistance. Drug Resist. Updates2:38-55.

5. Polyclonal Staphylococcal Endocarditis Caused by Genetic Variability

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