Involvement of the CYP1A1 inhibition-mediated activation of aryl hydrocarbon receptor in drug-induced hepatotoxicity
Author:
Affiliation:
1. Preclinical Research Unit, Sumitomo Pharma Co., Ltd.
2. Laboratory of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/47/9/47_359/_pdf
Reference59 articles.
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3. Chen, M., Vijay, V., Shi, Q., Liu, Z., Fang, H. and Tong, W. (2011): FDA-approved drug labeling for the study of drug-induced liver injury. Drug Discov. Today, 16, 697-703.
4. Chopra, M. and Schrenk, D. (2011): Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis-persistent pollutants affect programmed cell death. Crit. Rev. Toxicol., 41, 292-320.
5. Dalton, T.P., Puga, A. and Shertzer, H.G. (2002): Induction of cellular oxidative stress by aryl hydrocarbon receptor activation. Chem. Biol. Interact., 141, 77-95.
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