Utility of human cytochrome P450 inhibition data in the assessment of drug-induced liver injury
Author:
Affiliation:
1. School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan
2. Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan
Funder
Daiichi Sankyo Company
Publisher
Informa UK Limited
Link
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2024.2312505
Reference37 articles.
1. Minimizing the risk of chemically reactive metabolite formation of new drug candidates: implications for preclinical drug design
2. Risk Factors for Idiosyncratic Drug-Induced Liver Injury
3. DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans
4. Drug-Induced Liver Injury: Highlights and Controversies in the Recent Literature
5. Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework
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1. Improved Detection of Drug-Induced Liver Injury by Integrating Predicted In Vivo and In Vitro Data;Chemical Research in Toxicology;2024-07-09
2. Improved Detection of Drug-Induced Liver Injury by Integrating Predictedin vivoandin vitroData;2024-01-12
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