A 90-day repeated oral dose toxicity study of p-cymene in rats-Reference-Cited by-同舟云学术

A 90-day repeated oral dose toxicity study of p-cymene in rats

Published:2024 Issue:4 Volume:11 Page:169-181
ISSN:2189-115X
Container-title:Fundamental Toxicological Sciences
language:en
Short-container-title:Fundam. Toxicol. Sci.

Author:

Kuwagata Makiko¹,Doi Yuko²³,Saito Hirokatsu¹,Tsurumoto Mariko¹,Igarashi Toshime¹,Nishimura Takuya¹,Taquahashi Yuhji¹,Hirabayashi Yoko⁴,Kitajima Satoshi¹

Affiliation:

1. Division of Cellular and Molecular Toxicology, Center for Biological Safety and Research, National Institute of Health Sciences

2. DIMS Institute of Medical Science, Inc.

3. Toxicological Laboratory for Small Animals, BioSafety Research Center Inc.

4. Center for Biological Safety and Research, National Institute of Health Sciences

Publisher

Japanese Society of Toxicology

Link

https://www.jstage.jst.go.jp/article/fts/11/4/11_169/_pdf

Reference12 articles.

1. Adams, T.B., Gavin, C.L., McGowen, M.M., Waddell, W.J., Cohen, S.M., Feron, V.J., Marnett, L.J., Munro, I.C., Portoghese, P.S., Rietjens, I.M. and Smith, R.L. (2011): The FEMA GRAS assessment of aliphatic and aromatic terpene hydrocarbons used as flavor ingredients. Food Chem. Toxicol., 49, 2471-2494.

2. Api, A.M., Belsito, D., Biserta, S., Botelho, D., Bruze, M., Burton, G.A. Jr., Buschmann, J., Cancellieri, M.A., Dagli, M.L., Date, M., Dekant, W., Deodhar, C., Fryer, A.D., Gadhia, S., Jones, L., Joshi, K., Kumar, M., Lapczynski, A., Lavelle, M., Lee, I., Liebler, D.C., Moustakas, H., Na, M., Penning, T.M., Ritacco, G., Romine, J., Sadekar, N., Schultz, T.W., Selechnik, D., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y. and Tokura, Y. (2021): RIFM fragrance ingredient safety assessment, p-cymene, CAS Registry Number 99-87-6. Food Chem. Toxicol., 149 (Suppl 1), 112051.

3. Balahbib, A., El Omari, N., Hachlafi, N.E., Lakhdar, F., El Menyiy, N., Salhi, N., Mrabti, H.N., Bakrim, S., Zengin, G. and Bouyahya, A. (2021): Health beneficial and pharmacological properties of p-cymene. Food Chem. Toxicol., 153, 112259.

4. de Oliveira, T.M., de Carvalho, R.B., da Costa, I.H., de Oliveira, G.A., de Souza, A.A., de Lima, S.G. and de Freitas, R.M. (2015): Evaluation of p-cymene, a natural antioxidant. Pharm. Biol., 53, 423-428.

5. ECHA (2008): CLH report, Proposal for Harmonised Classification and Labelling based on Regulation (EC) No 1272/2008 (CLP Regulation), Annex VI, Part 2 Substance Name: 1-isopropyl-4-methylbenzene; ρ-cymene.