Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet-Reference-Cited by-同舟云学术

Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet

Published:2013 Issue:3 Volume:38 Page:379-390
ISSN:0388-1350
Container-title:The Journal of Toxicological Sciences
language:en
Short-container-title:J. Toxicol. Sci.

Author:

Watanabe Shiro¹,Tsuneyama Koichi²

Affiliation:

1. Division of Nutritional Biochemistry, Institute of Natural Medicine, University of Toyama

2. Department of Molecular Pathology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Link

https://www.jstage.jst.go.jp/article/jts/38/3/38_379/_pdf

Reference48 articles.

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3. Botham, K.M., Maldonado, E.N., Chico, Y., Zheng, X., Avella, M. and Ochoa, B. (2001): The influence of chylomicron remnants on cholesteryl ester metabolism in cultured rat hepatocytes: comparison of the effects of particles enriched in n-3 or n-6 polyunsaturated fatty acids. Biochim. Biophys. Acta, 1534, 96-109.

4. Chen, W., Suruga, K., Nishimura, N., Gouda, T., Lam, V.N. and Yokogoshi, H. (2005): Comparative regulation of major enzymes in the bile acid biosynthesis pathway by cholesterol, cholate and taurine in mice and rats. Life Sci., 77, 746-757.

5. Chiang, J.Y., Kimmel, R., Weinberger, C. and Stroup, D. (2000): Farnesoid X receptor responds to bile acids and represses cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription. J. Biol. Chem., 275, 10918-10924.

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