Lactoferrin promotes bile acid metabolism and reduces hepatic cholesterol deposition by inhibiting the farnesoid X receptor (FXR)-mediated enterohepatic axis-Reference-Cited by-同舟云学术

Lactoferrin promotes bile acid metabolism and reduces hepatic cholesterol deposition by inhibiting the farnesoid X receptor (FXR)-mediated enterohepatic axis

Published:2019 Issue:11 Volume:10 Page:7299-7307
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Ling Chen-Jie¹²³⁴⁵,Xu Jia-Ying⁶⁷³⁴⁵,Li Yun-Hong¹²³⁴⁵,Tong Xing¹²³⁴⁵,Yang Huan-Huan¹²³⁴⁵,Yang Jing⁸⁹⁴⁵,Yuan Lin-Xi¹⁰⁴⁵,Qin Li-Qiang¹²³⁴⁵^ORCID

Affiliation:

1. Department of Nutrition and Food Hygiene

2. School of Public Health

3. Soochow University

4. Suzhou 215123

5. China

6. State Key Laboratory of Radiation Medicine and Protection

7. School of Radiation Medicine and Protection

8. Department of Clinical Nutrition

9. The First Affiliated Hospital of Soochow University

10. Jiangsu Bio-Engineering Research Centre of Selenium

Abstract

Lactoferrin (LF) is a multifunctional glycoprotein that can regulate lipid metabolism, lower cholesterol, reduce body weight, and prevent atherosclerosis.

Funder

National Natural Science Foundation of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/FO/C9FO01616C

Reference40 articles.

1. Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis

2. Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis