Utilization of the repeated squat-stand model for studying the directional sensitivity of the cerebral pressure-flow relationship

Abstract

Repeated squat-stand maneuvers are able to examine the directional sensitivity of the cerebral pressure-flow relationship. These maneuvers induce stable physiological cyclic changes where brain blood flow changes with blood pressure increases are buffered more than blood pressure decreases. These results highlight the importance of considering directional blood pressure changes within cerebral autoregulation.