Synthesis and pharmacological evaluation of some benzylidene-4-nitroanilines-Reference-Cited by-同舟云学术

Synthesis and pharmacological evaluation of some benzylidene-4-nitroanilines

Published:2020-01-01 Issue:1 Volume:31 Page:55-59
ISSN:2286-038X
Container-title:Ovidius University Annals of Chemistry
language:en
Short-container-title:

Author:

Suresh Ramamurthy¹,Sakthinathan Saravanan Palanivel¹,Kamalakkannan Dakshnamoorthy¹,Muthuvel Inbasekaran²³,Thirunarayanan Ganesamoorthy²

Affiliation:

1. PG and Research Department of Chemistry , Government Arts College , C-Mutlur-608 102, Chidambaram , India

2. Department of Chemistry , Annamalai University , Annamalainagar - 608002 , India

3. Department of Chemistry , MR Government Arts College , Mannargudi - 614001 , India

Abstract

Abstract A number of nine benzylidene-4-nitroanilines were synthesized by condensation method. The formation of the substituted (E)-N-benzylidene-4-nitrobenzenamines has been confirmed from their physical and Ultra-Violet, Infra-Red, NMR spectral data. The evaluation of antimicrobial screening of substituted (E)-N-benzylidene-4-nitrobenzenamines was conducted by using standard Bauer-Kirby method. Three gram-positive microbes namely Bacillus subtilis, Micrococcus luteus and Staphylococcus aureus, and two gram-negative microbes, Escherichia coli and Pseudomonas aeruginosa, were used for the antibacterial evaluation. The antifungal activities against Aspergillus niger and Penicilium scup fungal species were also performed. A good antibacterial effect has been possessed by some of the substituted (E)-N-benzylidene-4-nitrobenzenamines on the microorganisms utilized in the present study

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

Link

https://www.sciendo.com/pdf/10.2478/auoc-2020-0011

Reference21 articles.

1. [1]. H. Schiff, H. Schiff, Mittheilungen aus dem Universitäts laboratorium in Pisa: Eine neue Reihe organischer Basen, J. Liebigs Annal. Chem. 131(1864) 118-119.

2. [2]. A.A.A. Abu-Hussen, Synthesis and spectroscopic studies on ternary bis-Schiff-base complexes having oxygen and/or nitrogen donors, J. Coord. Chem. 59 (2006) 157-176.

3. [3]. K. Singh, M. S. Barwa, P. Tyagi, Synthesis and characterization of cobalt(II), nickel(II), copper(II) and zinc(II) complexes with Schiff base derived from 4-amino-3-mercapto-6-methyl-5-oxo-1,2,4-triazine, Eur. J. Med. Chem. 42 (2007) 394-402.

4. [4]. P. Vicini, A. Geronikaki, M. Incerti, B. Busonera, G. Poni, C. A. Cabras, P. L. Colla, Synthesis and biological evaluation of benzo[d]isothiazole, benzothiazole and thiazole Schiff bases, Bioorg. Med. Chem. 11 (2003) 4785-4789

5. [5]. S. M. Sondhi, N. Singh, A. Kumar, O. Lozach, L. Meijer, Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff’s bases, Bioorg. Med. Chem. 14 (2006) 3758-3765.

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Ultrasound-assisted synthesis and spectral correlations of some bioactive E-imines;Research on Chemical Intermediates;2024-08-14

2. Ultrasound assisted synthesis and spectral correlations of some bio-active E-imines;2024-05-30

3. Synthesis, spectral study and evaluation of antibacterial activity of some novel 4-(6-methoxynaphthalen-2-yl)-6-(substituted aryl)pyrimidine-2(1H)-thiones;Ovidius University Annals of Chemistry;2024-01-01

4. Synthesis, spectral characterization, DFT-computational analyses on Novel 4-nitrobenzenaminium benzenesulfonate (4NBASA) crystal;Journal of Molecular Structure;2022-10

5. Ultrasound assisted synthesis and pharmacological evaluation of some (E)-1,2,3-triphenylprop-2-en-1-ones;Ovidius University Annals of Chemistry;2020-01-01