Ultrasound assisted synthesis and pharmacological evaluation of some (E)-1,2,3-triphenylprop-2-en-1-ones-Reference-Cited by-同舟云学术

Ultrasound assisted synthesis and pharmacological evaluation of some (E)-1,2,3-triphenylprop-2-en-1-ones

Published:2020-01-01 Issue:2 Volume:31 Page:152-157
ISSN:2286-038X
Container-title:Ovidius University Annals of Chemistry
language:en
Short-container-title:

Author:

Mala Veerendiran¹,Muthuvel Inbasekaran²³,Thirunarayanan Ganesamoorthy²,Sakthinathan Saravanan Palavanivel⁴,Arulkumaran Ranganathan⁴,Mani Venkatesan⁴,Sundararajan Rajasekaran⁴,Kamalakkannan Dakshnamoorthy⁴,Suresh Ramamurthy⁴,Usha Veeramalai⁵

Affiliation:

1. Department of Chemistry , Annai Arts & Science College , Kovilacheri, Kumbakonam-612 503 , India

2. Department of Chemistry , Annamalai University , Annamalainagar-608 002 , India

3. Department of Chemistry , MR Government Arts College , Mannargudi-614 001 , India

4. Postgraduate and Research Department of Chemistry , Government Arts College , C-Mutlur-608102, Chidambaram , India

5. Department of Chemistry , University College of Engineering , Panruti - , India

Abstract

Abstract More than 85% yield of (E)-1,2,3-triphenylprop-2-en-1-ones were synthesized using disodium hydrogen phosphate (Na2HPO4) catalyzed ultrasound assisted aldol condensation of 1,2-diphenylethanone and various substituted benzaldehydes. Synthesized (E)-1,2,3-triphenylprop-2-en-1-ones were examined by their spectroscopic data, yield, micro analysis and physical constants. The effect of solvent on the yield was investigated. The pharmacological effects such as antibacterial and antifungal activities of synthesized enones were evaluated with Bauer-Kirby disc diffusion method.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

Link

https://www.sciendo.com/pdf/10.2478/auoc-2020-0024

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