Affiliation:
1. Department of Pharmacy, Drug Design Group, University of Groningen
2. Department of Chemistry, University of Crete
Abstract
AbstractFluorene and fluorenone are privileged structures with extensive utility in both materials science and drug discovery. Here, we describe syntheses of those moieties through isocyanide-based multicomponent reactions (IMCRs) and the incorporation of the products in diverse and complex derivatives that can be further utilized. We performed six different IMCRs, based on the dual functionality of 9-isocyano-9H-fluorene, and we describe 23 unprecedented adducts.
Funder
H2020 Marie Sklodowska-Curie Actions
Qatar National Research Fund
Hellenic Foundation for Research and Innovation
China Scholarship Council
Cited by
8 articles.
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