Molecular Construction Using Formamide as a C1 Feedstock

Author:

Sacchelli Bruce A. L.1ORCID,Rocha Bianca C.1ORCID,Fantinel Mariane1,Andrade Leandro H.1ORCID

Affiliation:

1. Departamento de Química Fundamental, Instituto de Química Universidade de São Paulo Av. Prof. Lineu Prestes, 748 – Butantã São Paulo SP 05508-900 Brazil

Abstract

AbstractFormamide (HCONH2), a well‐known organic compound in chemistry and biology, can be employed for molecular construction. The chemistry of formamide, which involves condensation reactions, transamidation reactions, cross‐coupling reactions, and radical reactions, can be explored to synthesize more complex organic compounds. The focus of this review is to discuss the widespread use of formamide as a relevant C‐1 building block in organic synthesis.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Wiley

Subject

Organic Chemistry,Physical and Theoretical Chemistry

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