Access to Isoquinolin-2(1<i>H</i>)-yl-acetamides and Isoindolin-2-yl-acetamides from a Common MCR Precursor-Reference-Cited by-同舟云学术

Access to Isoquinolin-2(1H)-yl-acetamides and Isoindolin-2-yl-acetamides from a Common MCR Precursor

Published:2022-10-25 Issue:21 Volume:87 Page:14463-14475
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Li Xin¹,Wang Qian¹,Zheng Qiang¹,Kurpiewska Katarzyna²,Kalinowska-Tluscik Justyna²^ORCID,Dömling Alexander¹^ORCID

Affiliation:

1. Department of Drug Design, University of Groningen, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands

2. Faculty of Chemistry, Department of Crystal Chemistry and Crystal, Physics, Biocrystallography Group, Jagiellonian University, Gronostajowa 2, 30-387 Krakow, Poland

Funder

China Scholarship Council

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.2c01905

Reference37 articles.

1. Multicomponent Reaction Design in the Quest for Molecular Complexity and Diversity

2. Ugi/Aldol Sequence: Expeditious Entry to Several Families of Densely Substituted Nitrogen Heterocycles

3. Structurally Diverse Polyamides Obtained from Monomers Derived via the Ugi Multicomponent Reaction

4. Discovery of amide replacements that improve activity and metabolic stability of a bis-amide smoothened antagonist hit

5. Isoquinolone-4-Carboxylic Acids by Ammonia-Ugi-4CR and Copper-Catalyzed Domino Reaction

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