CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells-Reference-Cited by-同舟云学术

CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells

Published:2022-06-20 Issue:12 Volume:6 Page:3626-3631
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Ansari Unain¹^ORCID,Tomellini Elisa¹,Chagraoui Jalila¹,Lehnertz Bernhard¹,Mayotte Nadine¹,Bordeleau Marie-Eve¹,Roux Philippe P.²³^ORCID,Sauvageau Guy¹⁴⁵

Affiliation:

1. 1Molecular Genetics of Stem Cells Laboratory, Institute for Research in Immunology and Cancer,

2. 2Cell Signalling and Proteomics Research Unit, Institute for Research in Immunology and Cancer, and

3. 3Department of Pathology and Cell Biology, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada;

4. 4Division of Hematology, Maisonneuve-Rosemont Hospital, Montréal, QC, Canada; and

5. 5Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada

Abstract

Key Points CEACAM1 is a novel cell surface marker of ex vivo expanded LT-HSCs. Sorting umbilical cord blood cells based on CEACAM1 and known HSC marker expression allows purification of LT-HSCs with improved purity.

Publisher

American Society of Hematology

Subject

Hematology

Link

https://ashpublications.org/bloodadvances/article-pdf/6/12/3626/1902627/advancesadv2021006835.pdf

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