A 4-lncRNA scoring system for prognostication of adult myelodysplastic syndromes

Author:

Yao Chi-Yuan123,Chen Ching-Hsuan4,Huang Huai-Hsuan1,Hou Hsin-An1,Lin Chien-Chin123,Tseng Mei-Hsuan1,Kao Chein-Jun1,Lu Tzu-Pin4,Chou Wen-Chien12,Tien Hwei-Fang1

Affiliation:

1. Division of Hematology, Department of Internal Medicine, and

2. Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan; and

3. Graduate Institute of Clinical Medicine, College of Medicine, and

4. Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan

Abstract

Key Points Through lncRNA profiling, we identified an MDS patient subset with distinct clinical and mutational patterns along with inferior outcomes. A concise yet powerful 4-lncRNA risk-scoring system was devised with the potential to improve current MDS risk stratification.

Publisher

American Society of Hematology

Subject

Hematology

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