Cartilage oligomeric matrix protein is a natural inhibitor of thrombin-Reference-Cited by-同舟云学术

Cartilage oligomeric matrix protein is a natural inhibitor of thrombin

Published:2015-08-13 Issue:7 Volume:126 Page:905-914
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Liang Ying¹²,Fu Yi¹²,Qi Ruomei³,Wang Meili¹²,Yang Nan¹²,He Li¹²,Yu Fang¹²,Zhang Jian⁴,Yun Cai-Hong⁵,Wang Xian¹²,Liu Junling⁶,Kong Wei¹²

Affiliation:

1. Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University, Peking, People’s Republic of China;

2. Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, People’s Republic of China;

3. Key Laboratory of Geriatrics, Beijing Hospital and Beijing Institute of Geriatrics, Ministry of Health, Beijing, People’s Republic of China;

4. Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China;

5. Department of Biophysics, School of Basic Medical Sciences, Peking University, Beijing, People’s Republic of China; and

6. Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, Shanghai, People’s Republic of China

Abstract

Key Points COMP negatively regulates hemostasis and thrombosis. COMP is a natural inhibitor of thrombin.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/126/7/905/1391085/905.pdf

Reference40 articles.

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4. Cartilage matrix proteins. An acidic oligomeric protein (COMP) detected only in cartilage.;Hedbom;J Biol Chem,1992

5. Thrombospondins in physiology and disease: new tricks for old dogs.;Murphy-Ullrich;Matrix Biol,2012

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