TLR1/2-stimulated DCs “prime” HSCs via IL-1β
Author:
Affiliation:
1. 1University Hospital Zurich
2. 2University of Zurich
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
https://ashpublications.org/blood/article-pdf/140/14/1576/1923588/blood_bld-2022-017137-c-main.pdf
Reference10 articles.
1. IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function;Li;Blood,2022
2. Inflammation as a regulator of hematopoietic stem cell function in disease, aging, and clonal selection;Caiado;J Exp Med,2021
3. Pathogen-induced TLR4-TRIF innate immune signaling in hematopoietic stem cells promotes proliferation but reduces competitive fitness;Takizawa;Cell Stem Cell,2017
4. Bone marrow CX3CR1+ mononuclear cells relay a systemic microbiota signal to control hematopoietic progenitors in mice;Lee;Blood,2019
5. Systemic TLR2 agonist exposure regulates hematopoietic stem cells via cell-autonomous and cell-non-autonomous mechanisms;Herman;Blood Cancer J,2016
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