Diastereoselective synthesis of spiro[cyclopropane-1,3′-indolin]-2′-ones through metal-free cyclopropanation using tosylhydrazone salts-Reference-Cited by-同舟云学术

Diastereoselective synthesis of spiro[cyclopropane-1,3′-indolin]-2′-ones through metal-free cyclopropanation using tosylhydrazone salts

Published:2014 Issue:72 Volume:4 Page:38425-38432
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Kapure Jeevak Sopanrao¹²³⁴⁵,Reddy Chada Narsimha¹²³,Adiyala Praveen Reddy¹²³,Nayak Ranjita¹²³,Nayak V. Lakshma¹²³,Nanubolu Jagadeesh Babu⁶⁷³,Singarapu Kiran Kumar⁸²³,Maurya Ram Awatar¹²³

Affiliation:

1. Division of Medicinal Chemistry and Pharmacology

2. CSIR-Indian Institute of Chemical Technology

3. Hyderabad, India

4. Department of Medicinal Chemistry

5. National Institute of Pharmaceutical Education and Research

6. Centre for X-ray Crystallography

7. Indian Institute of Chemical Technology

8. Centre for Nuclear Magnetic Resonance

Abstract

Anticancer spiro[cyclopropane-1,3′-indolin]-2′-ones are accessible through a transition metal-free diastereoselective cyclopropanation using in situ generated diazo-compounds.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA05755D

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